SOLUBLE ANALYTE AMPLIFICATION (SAM)

 

Description

 Although clinical diagnostic tests have changed the face of healthcare, current products on the market do not have the level of detection capabilities to detect biomarkers at the low levels observed early in disease. Soluble Analyte Amplification, (SAM) makes the ultrasensitive detection of disease biomarkers possible and allows the detection of disease earlier on when treatment is more efficacious.

By combining novel antibodies with SAM technology, Restalyst will be in the position to offer new diagnostic capabilities to the marketplace. SAM technology can detect proteins to attomolar (aM) concentrations in biological fluids, at least a million times more sensitive than current rapid, immunoassay, antigen detection technologies.


SAM TECHNOLOGY HAS MAJOR ADVANTAGES OVER OTHER PROTEIN TECHNOLOGY PLATFORMS...

 

SAM is an ultrasensitive protein technology- it can detect to attomolar (aM) concentrations.
SAM detects and assays for antigen in the solution phase without solid phase capture. Binding in the solution phase is faster than binding constrained by surface interactions with immobilized antibodies.
SAM uses one binding construct (antibody); there is no need to sandwich antigen or to develop antibody or binding pairs for detection.
Uniquely, SAM does not ‘use up’ sample required for further analysis.
SAM requires no capital equipment purchase for labs with existing PCR capabilities.
SAM can be easily adapted to multi-sample and high-throughput platforms.
For applications that do not require high sensitivity, SAM can be adapted to fluorescent and enzymatic detection platforms.


FOR A SCHEMATIC OF SAM TECHNOLOGY, PLEASE CLICK HERE   

 

Soluble Analyte Amplification (SAM) ability to detect extremely low levels of protein in a single or multiplexed format allows it to have potentially limitless applications in clinical, diagnostic or research markets including neurology, oncology, infectious disease and cardiovascular disease.
Please contact us to learn more about the ultra-sensitive detection possibilities of SAM.